Better patient management with HCV RNA testing

For both interferon-based and interferon-free DAA therapies, HCV RNA
testing continues to be a critical assessment tool to:

The efficacy of antiviral therapies can be assessed by measuring the level of viral suppression during and after treatment.

  • Repeated measurements of HCV RNA levels help determine the effectiveness of all HCV therapy options1

Full adherence to HCV antiviral therapy is essential in order for patients to achieve a sustained virological response (SVR).2

  • Measuring HCV RNA can help assess patient adherence to therapy and keep patients motivated to continue treatment

Although new DAAs are highly effective in treating HCV, it remains possible that some patients may relapse.

  • HCV RNA testing allows clinicians to monitor patients for potential relapse following HCV treatment

HCV RNA testing is not limited to response-guided therapy or evaluation of futility
and remains important with next-generation DAAs.

References:

1.
European Association for the Study of the Liver. EASL Recommendations on Treatment of Hepatitis C 2014. J Hepatol. 2014 Aug;61(2):373-95.
2.
Evon DM, Golin CE, Bonner JE, et al. Adherence during antiviral treatment regimens for chronic hepatitis C: a qualitative study of patient-reported facilitators and barriers. J Clin Gastroenterology. 2014 May; PMID 24828358 [Epub ahead of print].